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Table 4 Multivariate analysis of significant prognostic factors identified by univariate analysis

From: Rectal cancer level significantly affects rates and patterns of distant metastases among rectal cancer patients post curative-intent surgery without neoadjuvant therapy

   Overall survival Disease-free survival
Variables   HR 95.0% CI for HR P HR 95.0% CI for HR P
Age   1.026 1.017-1.035 <0.001 - - -
Sex        
  Female 1 - - - - -  
  Male 1.260 1.019-1.558 0.033 - - -  
Location along the rectum        
  10.1-15 cm 1     1   
  5.1-10 cm 1.315 1.044-1.657 0.020 1.570 1.224-2.014 <0.001  
  0-5 cm 2.284 1.69-3.03 <0.001- 2.780 2.038-3.792 <0.001  
TMN_T        
  T3 1 - - 1 - -  
  T4 1.480 1.195-1.835 <0.001 1.593 1.268-2.001 <0.001  
TMN_N        
  N0 1 - - 1 - -  
  N1 1.693 1.296-2.211 <0.001 2.194 1.623-2.966 <0.001  
  N2-N3 2.454 1.902-3.166 <0.001 3.377 2.543-4.485 <0.001  
HG        
  Well 1 - - 1 - -  
  Mod 0.891 0.622-1.287 0.530 1.056 0.695-1.604 0.798  
  Poor 1.710 1.008-2.899 0.047 2.044 1.152-3.627 0.015