From: MicroRNA-9 expression is a prognostic biomarker in patients with osteosarcoma
Clinicopathological features | Number of cases | miR-9 expression | P value | |
---|---|---|---|---|
High ( n, %) | Low ( n, %) | |||
Age | ||||
<50 | 41 | 23 (56.1%) | 18 (43.9%) | 0.879 |
≥50 | 38 | 17 (44.7%) | 21 (55.3%) | |
Gender | ||||
Male | 44 | 25 (56.8%) | 19 (43.2%) | 0.636 |
Female | 35 | 15 (42.9%) | 20 (57.1%) | |
Anatomical location | ||||
Tibia/femur | 51 | 26 (51.0%) | 25 (49.0%) | 0.901 |
Elsewhere | 28 | 14 (50.0%) | 14 (50.0%) | |
Tumor size (cm) | ||||
<8 | 48 | 17 (35.4%) | 31 (64.6%) | |
≥8 | 31 | 23 (74.2%) | 8 (25.8%) | 0.011 |
Clinical stage | ||||
I/II | 39 | 9 (23.1%) | 30 (76.9%) | |
III | 40 | 31 (77.5%) | 9 (22.5%) | 0.009 |
Pathological fracture | ||||
Present | 11 | 6 (54.5%) | 5 (45.4%) | |
Absent | 68 | 34 (50.0%) | 34 (50.0%) | 0.899 |
Distant metastasis | ||||
Present | 19 | 17 (89.5%) | 2 (10.5%) | |
Absent | 60 | 21 (35.0%) | 39 (65.0%) | <0.001 |