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Table 1 Clinicopathologic features, treatment, and prognosis of seven cases of primary synovial sarcoma of prostate

From: Primary synovial sarcoma of the prostate metastatic to the liver and lung: a case report

  Cases
  Iwasaki Shirakawa Williams Pan Li first case Li second case This study
Age (years) 37 52 63 44 46 44 22
Clinical findings Gross hematuria, dysuria, painful micturition Urinary retention Lower urinary tract symptoms Lower urinary tract symptoms Dysuria, painful micturition Dysuria gradually Dysuria, urinary frequency, nocturia, urinary retention
Serum PSA (ng/ml) None 0.9 0.5 2.91 0.35 1.19 1.2
Extent of tumor 10-cm solid mass with necrosis, invading the prostatic urethra, seminal vesicles, retrovesical soft tissues 7-cm mass, originating in the prostatic fascia of the right lobe 8.5-cm mass extending from the mid-potion of the prostate inferiorly to the base of the penis 6-cm, well circumscribed, soft, heterogeneous mass in the right side of prostate 5.5-cm mass with partial necrosis extending to the pelvic soft tissue 12-cm mass extending to the bladder, the rectum and pelvic soft tissue, partial necrosis 14-cm mass that appeared to originate in the prostatic fascia. Another 8.5-cm mass was found in the right groin area
IHC results VM+, EMA + VM+ VM+, CK(CAM5.2)+, S100+, CK7+, CKAE1/3+,CAL+ VM+, CD99+, CK +, bcl-2+ VM+, CD99+, bcl-2+, E-CA+, CK/EMA + VM+, CK+,CD99+, E-CA+, bcl-2+ VM+, CD99+
Treatment Chemotherapy, radical prostatocystectomy Radical prostatectomy, adjuvant chemotherapy Irradiation with en bloc penectomy and pubectomy and ileal conduit urinary diversion Radical prostatectomy Radical prostatectomy, chemotherapy The tumor could not be completely resected None
Prognosis Died (32 months, tumor recurrence and metastasis to the lungs and liver) Alive (no recurrence or metastasis) Alive (no recurrence or metastasis) Alive (no recurrence and metastasis) Alive (no recurrence and metastasis) Died (eight months, tumor recurrence and metastasis to the costosternal junction and lung) Died (three months, multiple lung metastasis and respiratory failure