Table 2 Independent prognostic factors for disease-free and overall survival by multivariate analysis
From: Lesson from 610 liver resections of hepatocellular carcinoma in a single center over 10 years
Variable | Coefficient | Standard error | P-value | Relative risk (95% CI) |
|---|---|---|---|---|
Disease-free survival | ||||
AST (>50 IU/L) | 0.381 | 0.136 | 0.016 | 1.379 (1.062 to 1.789) |
Liver cirrhosis | 0.296 | 0.119 | 0.043 | 1.292 (1.009 to 1.654) |
Perioperative transfusion | 0.301 | 0.118 | 0.008 | 1.386 (1.090 to 1.763) |
Multiple tumors | 0.553 | 0.134 | 0.013 | 1.564 (1.097 to 2.230) |
Microvascular invasion | 0.382 | 0.128 | < 0.001 | 1.604 (1.255 to 2.050) |
Edmondson-Steiner grade III to IV | 0.321 | 0.131 | 0.014 | 1.379 (1.066 to 1.784) |
Overall survival | ||||
Serum albumin (≤3.5 g/dL) | 0.587 | 0.166 | < 0.001 | 1.798 (1.298 to 2.490) |
Platelet count (≤100,000/mm3) | 0.442 | 0.167 | 0.008 | 1.557 (1.122 to 2.161) |
Perioperative transfusion | 0.477 | 0.140 | 0.001 | 1.610 (1.224 to 2.118) |
Perioperative morbidity | 0.353 | 0.143 | 0.013 | 1.423 (1.076 to 1.883) |
Tumor size (>3 cm) | 0.313 | 0.154 | 0.043 | 1.367 (1.010 to 1.850) |
Multiple tumors | 0.679 | 0.147 | < 0.001 | 1.973 (1.478 to 2.633) |
Macrovascular invasion | 0.581 | 0.227 | 0.011 | 1.789 (1.145 to 2.793) |
Edmondson-Steiner grade III to IV | 0.419 | 0.147 | 0.004 | 1.521 (1.141 to 2.028) |