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Table 2 Independent prognostic factors for disease-free and overall survival by multivariate analysis

From: Lesson from 610 liver resections of hepatocellular carcinoma in a single center over 10 years

Variable Coefficient Standard error P-value Relative risk (95% CI)
Disease-free survival     
 AST (>50 IU/L) 0.381 0.136 0.016 1.379 (1.062 to 1.789)
 Liver cirrhosis 0.296 0.119 0.043 1.292 (1.009 to 1.654)
 Perioperative transfusion 0.301 0.118 0.008 1.386 (1.090 to 1.763)
 Multiple tumors 0.553 0.134 0.013 1.564 (1.097 to 2.230)
 Microvascular invasion 0.382 0.128 < 0.001 1.604 (1.255 to 2.050)
 Edmondson-Steiner grade III to IV 0.321 0.131 0.014 1.379 (1.066 to 1.784)
Overall survival     
 Serum albumin (≤3.5 g/dL) 0.587 0.166 < 0.001 1.798 (1.298 to 2.490)
 Platelet count (≤100,000/mm3) 0.442 0.167 0.008 1.557 (1.122 to 2.161)
 Perioperative transfusion 0.477 0.140 0.001 1.610 (1.224 to 2.118)
 Perioperative morbidity 0.353 0.143 0.013 1.423 (1.076 to 1.883)
 Tumor size (>3 cm) 0.313 0.154 0.043 1.367 (1.010 to 1.850)
 Multiple tumors 0.679 0.147 < 0.001 1.973 (1.478 to 2.633)
 Macrovascular invasion 0.581 0.227 0.011 1.789 (1.145 to 2.793)
 Edmondson-Steiner grade III to IV 0.419 0.147 0.004 1.521 (1.141 to 2.028)
  1. AST, aspartate aminotransferase; CI, confidence interval.