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Figure 3 | World Journal of Surgical Oncology

Figure 3

From: Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors

Figure 3

Upregulation of β-catenin and anti-apoptotic protein Mcl-1 in response to OPN in GIST cell lines resistant to imatinib. (A) Western blotting analysis of GIST48B and GIST62 cell lines treated with imatinib (1 μM) or OPN (2 μg/mL). (B) Quantification of the western blots showing significant changes in the expression of β-catenin and anti-apoptotic protein Mcl-1 in relation to OPN administration in GIST48B and GIST62 (Columns, mean of results in triplicate; bars, SD. *, P <0.05).

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