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Table 2 Diagnostic performance of mammography and mammography with computer-aided detection (CAD) for normal plus microcalcification cases (n = 70)

From: Who could benefit the most from using a computer-aided detection system in full-field digital mammography?

Readers

Sensitivity

Specificity

PPV

NPV

Total (n = 20)

Mammography

Mammo + CAD

Mammography

Mammo + CAD

Mammography

Mammo + CAD

Mammography

Mammo + CAD

BR (n = 7)

93.33 ± 10.18

95.24 ± 5.04

75.59 ± 11.35

78.70 ± 11.10

52.96 ± 12.69

57.18 ± 11.89

97.29 ± 4.51

98.33 ± 1.75

RR (n = 13)

87.69 ± 13.29

87.69 ± 11.50

78.32 ± 7.62

73.71 ± 10.70

53.44 ± 8.40

49.46 ± 11.42

96.20 ± 3.98

95.56 ± 4.24

BR subgroups

 

Ex ≥10* (n = 3)

97.78 ± 3.85

97.78 ± 3.85

80.61 ± 8.20

81.82 ± 5.46

59.14 ± 11.06

60.03 ± 7.45

99.26 ± 1.28

99.28 ± 1.25

Ex <10* (n = 4)

90.00 ± 12.77

93.33 ± 5.44

71.82 ± 12.98

76.36 ± 14.47

48.32 ± 13.18

55.05 ± 15.22

95.81 ± 5.72

97.62 ± 1.88

CAD ex (n = 5)

97.33 ± 5.96

96.00 ± 5.96

79.27 ± 6.37

82.54 ± 6.25

56.99 ± 9.17

61.02 ± 9.48

99.07 ± 2.08

98.72 ± 1.96

no CAD ex (n = 2)

83.33 ± 14.14

93.33 ± 0

66.37 ± 19.28

69.09 ± 18.00

42.87 ± 18.58

47.59 ± 15.20

92.83 ± 7.00

97.36 ± 0.67

RR subgroups

 

RR(non-trained) (n = 6)

87.78 ± 12.23

84.44 ± 10.04

80.00 ± 8.83

74.24 ± 14.29

55.92 ± 10.82

50.37 ± 16.2

96.19 ± 3.63

94.13 ± 4.30

RR(trained) (n = 7)

87.62 ± 15.12

90.48 ± 12.68

76.88 ± 6.78

73.25 ± 7.62

51.32 ± 5.69

48.69 ± 6.39

96.21 ± 4.56

96.79 ± 4.08

  1. Note.―All data are the percentages.
  2. *Ex ≥10 means that the reviewer’s experience with breast imaging equal to or more than 10 years, while Ex <10 less than 10 years.
  3. BR, dedicated breast radiologists; ex, experience; mammo, mammography; NPV, negative predictive value; PPV, positive predictive value; RR, radiology residents.