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Table 3 Multivariate regression analysis for cancer recurrence of stage III colon cancer

From: Inferior oncological prognosis of surgery without oral chemotherapy for stage III colon cancer in clinical settings

Variable

Comparison

Multivariate

HR

95% CI

P value

Age

 

1

0.968 to 1.036

0.941

Comorbidity

No versus yes

0.96

0.490 to 1.864

0.895

ASA (grade ≥3)

No versus yes

1.34

0.452 to 3.994

0.595

Location

Right versus left side of colon

1.08

0.561 to 2.089

0.81

Serum CEA

<5 versus ≥5

0.61

0.316 to 1.167

0.135

Operation

Laparoscopic versus open surgery

1.08

0.503 to 2.301

0.85

Morbidity

No versus yes

0.64

0.189 to 2.154

0.47

Tumor depth

T1, 2 versus T3, 4

0.17

0.037 to 0.801

0.03

Lymph node metastasis

N1 (1 to 3) versus N2 (4<)

0.56

0.244 to 1.268

0.16

TNM stage

IIIA, B versus IIIC

0.29

0.106 to 0.785

0.02

Adjuvant chemotherapy

No versus yes

3.23

1.458 to 7.159

0.004

  1. CEA, carcinoembryonic antigen; CI, confidence interval; HR, hazard ratio.