Variable | Surgery (n = 88) | Adjuvant chemotherapy (n = 171) | P value |
---|---|---|---|
Gender | 0.78 | ||
Female | 38 | 77 | |
Male | 50 | 79 | |
Age (years, mean) | 75.4 | 63.4 | <0.0001 |
Comorbidity | 60 (68%) | 82 (47%) | 0.002 |
ASA (grade ≥3) | 27 (30%) | 2 (1%) | <0.0001 |
Location | |||
Right side of colon | 36 | 62 | 0.47 |
Left side of colon | 52 | 109 | |
Colon | 77 | 136 | 0.11 |
Rectosigmoid | 11 | 35 | |
Serum CEA | |||
≥5 | 36 (41%) | 73 (43%) | 0.78 |
≥10 | 19 (22%) | 43 (25%) | 0.53 |
Postoperative hospital stay (mean) | 10.8 | 8.9 | 0.08 |
Histological type | |||
Differentiated | 79 | 156 | 0.7 |
Undifferentiated | 9 | 15 | |
Lymphovascular invasion (≥2, 3) | 26 (30%) | 46 (27%) | 0.65 |
Tumor depth | |||
T1/T2/T3/T4 | 13/5/52/18 | 9/15/113/34 | 0.06 |
Lymph node metastasis | |||
N1 (1 to 3) | 65 | 131 | 0.33 |
N2 (4≤) | 23 | 40 | |
Lymph node number (≥12) | 81 (92%) | 161 (94%) | 0.52 |
TNM stage | |||
IIIA/IIIB/IIIC | 16/60/11 | 22/127/22 | 0.380 |
Rejected reasons of adjuvant chemotherapy | |||
Older person (>80 years) | 37 (42%) | ||
Self-judgment | 29 (33%) | ||
Severe comorbidities | 16 (18%) | ||
Postoperative complications | 6 (7%) |