Skip to main content

Table 1 Comparison of patient characteristics stratified according to receipt of adjuvant chemotherapy and rejected reasons of adjuvant chemotherapy

From: Inferior oncological prognosis of surgery without oral chemotherapy for stage III colon cancer in clinical settings

Variable

Surgery (n = 88)

Adjuvant chemotherapy (n = 171)

P value

Gender

  

0.78

  Female

38

77

 

  Male

50

79

 

Age (years, mean)

75.4

63.4

<0.0001

Comorbidity

60 (68%)

82 (47%)

0.002

  ASA (grade ≥3)

27 (30%)

2 (1%)

<0.0001

Location

   

  Right side of colon

36

62

0.47

  Left side of colon

52

109

 

  Colon

77

136

0.11

  Rectosigmoid

11

35

 

Serum CEA

   

  ≥5

36 (41%)

73 (43%)

0.78

  ≥10

19 (22%)

43 (25%)

0.53

Postoperative hospital stay (mean)

10.8

8.9

0.08

Histological type

   

  Differentiated

79

156

0.7

  Undifferentiated

9

15

 

Lymphovascular invasion (≥2, 3)

26 (30%)

46 (27%)

0.65

Tumor depth

   

  T1/T2/T3/T4

13/5/52/18

9/15/113/34

0.06

Lymph node metastasis

   

  N1 (1 to 3)

65

131

0.33

  N2 (4≤)

23

40

 

Lymph node number (≥12)

81 (92%)

161 (94%)

0.52

TNM stage

   

  IIIA/IIIB/IIIC

16/60/11

22/127/22

0.380

Rejected reasons of adjuvant chemotherapy

  

  Older person (>80 years)

37 (42%)

  

  Self-judgment

29 (33%)

  

  Severe comorbidities

16 (18%)

  

  Postoperative complications

6 (7%)

  
  1. ASA, American Society of Anesthesiologists physical status classification system; CEA, carcinoembryonic antigen; TNM, tumor, node, metastasis.