Skip to main content

Table 1 ECM1 expression, LMVD, and clinicopathological characteristics

From: Extracellular matrix protein 1 is correlated to carcinogenesis and lymphatic metastasis of human gastric cancer

Clinicopathological parameters

N

 

ECM1 expression

 

LMVD

 

-

+

P

(LMV per × 200 field)

P

Gender

   

0.618

 

0.627

Male

47

13

34

 

7.76 ± 1.21

 

Female

30

10

20

 

7.83 ± 1.23

 

Age (years)

   

0.628

 

0.553

<60

37

10

27

 

7.25 ± 1.17

 

≥60

40

13

27

 

8.34 ± 1.33

 

Differentiation degree

   

0.489

 

0.253

Low

36

11

25

 

9.25 ± 1.37

 

Moderate

23

5

18

 

5.75 ± 1.22

 

Well

18

7

11

 

7.94 ± 2.01

 

Depth of invasion

   

<0.0001***

 

0.721

T1-T2

23

18

5

 

8.77 ± 1.97

 

T3-T4

54

5

49

 

7.53 ± 0.99

 

Lymph node metastasis

   

0.521

 

0.110

0

34

9

25

 

6.74 ± 1.29

 

1-2

18

9

11

 

7.00 ± 2.46

 

3-6

10

3

7

 

11.00 ± 2.74

 

≥7

15

4

11

 

9.57 ± 1.47

 

TNM stage

   

0.0014**

 

0.241

0-I

21

12

9

 

8.50 ± 2.12

 

II-III

27

11

45

 

8.67 ± 1.18

 
  1. ‘+’, ‘++’, and ‘+++’ for ECM1 IHC staining are grouped together as ‘+’.
  2. T1: lamina propria and submucosa; T2: muscularis propria and subserosa; T3: exposure to serosa; T4: invasion into serosa.
  3. **P <0.01.
  4. ***P <0.001.
  5. P <0.05 is considered statistically significant.