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Table 1 Review of head and neck (except for lymph node) metastases from mesothelioma published in the literature

From: Malignant pleural mesothelioma metastatic to the submandibular salivary gland, simulating glandular hypertrophy, diagnosed by fine-needle aspiration biopsy: a case report and literature review

Site of metastasis Number of patients Clinical presentation Diagnostic modality References
Tongue 7 Tongue lesion, nodular consolidation of the tongue with chronic bleeding, submucosal mass, horizontal fissure, swelling of the dorsal surface of the tongue, polypoid lesion Surgery, lingual incisional and excisional biopsy [5, 7, 10, 1416, 18]
Mandible 4 Radicular cyst, mandibular gingival mass, periapical radiolucency Excision of the tooth, biopsy, incisional biopsy, excision of the mass [5, 6, 8, 12]
Oral mucosa 3 Submucosal mass Biopsy [11, 17, 19]
Lips 1 Lip lesion Lip biopsy [9]
Conjunctiva 1 n/a n/a [11]
Thyroid 1 n/a n/a [11]
Total 17    
  1. We collected the previously published cases of metastases from mesothelioma to the head and neck area, except for lymph node metastases. Tongue was the most frequent site of metastases, with different clinical presentations; no metastases to the salivary glands had previously been found, and no diagnoses of metastases with FNAB had been made.