| Overall survival | ||||||
---|---|---|---|---|---|---|---|
Univariate | Multivariate | ||||||
Variable | n | HR | 95% CI | P | HR | 95% CI | P |
Age/10Â y | 253 | 1.32 | (1.12, 1.54) | <0.001 | 1.29 | (1.08, 1.54) | 0.005 |
DFI, months | 253 | 0.91 | (0.80, 1,03) | 0.122 | 0.91 | (0.79, 1.05) | 0.187 |
Number of metastases | 253 | 1.19 | (1.10, 1.28) | <0.001 | 1.31 | (1.17, 1.45) | <0.001 |
Metastasis diam, cm | 242 | 1.11 | (1.03, 1.19) | 0.006 | 1.09 | (1.02, 1.18) | 0.023 |
RM status  R0 | 205 | 1.00 | Reference |  | 1.00 | Reference |  |
      R1 | 48 | 1.69 | (1.14, 2.51) | 0.014 | 1.53 | (0.98, 2.39) | 0.067 |
T stage | Â | Â | Â | 0.931 | Â | Â | 0.897 |
      T2 | 25 | 1.00 | Reference |  | 1.00 | Reference |  |
      T3 | 180 | 1.10 | (0.65, 1.87) |  | 0.99 | (0.54, 1.81) |  |
      T4 | 34 | 1.11 | (0.57, 2.19) |  | 0.88 | (0.40, 1.90) |  |
N stage | Â | Â | Â | 0.506 | Â | Â | 0.229 |
      N0 | 91 | 1.00 | Reference |  | 1.00 | Reference |  |
      N1 | 103 | 1.19 | (0.83, 1.72) |  | 1.32 | (0.88, 1.98) |  |
      N2 | 51 | 1.27 | (0.81, 1.98) |  | 1.49 | (0.92, 2.42) |  |
ASA score | 253 | 1.62 | (1.20, 2.19) | 0.002 | 1.61 | (1.13, 2.29) | 0.009 |
Bilobar   No | 159 | 1.00 | Reference |  | 1.00 | Reference |  |
      Yes | 94 | 1.38 | (1.01, 1.89) | 0.048 | 1.22 | (0.80, 1.86) | 0.353 |
Re-resections | Â | 0.78 | (0.60, 1.01) | 0.045 | 0.71 | (0.52, 0.97) | 0.016 |