Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival

Table 3 Results from multinomial logistic regression of recurrence according to resection margins (RMs) in n = 242 patients with known recurrence status after primary resection for colorectal liver metastases

Recurrence^†	RM	OR	95% CI	P value
Local	R1, <1 mm	24.89	(4.77, 129.69)	0.0001
(n = 40)	1-4 mm	16.00	(3,22, 79.56)	0.001
	5-9 mm	5.25	(0.95, 29.15)	0.058
	≥10 mm	1.00	Reference
Hepatic only	R1, <1 mm	1.13	(0.38, 3.42)	0.827
(n = 52)	1-4 mm	1.36	(0.55, 3.41)	0.508
	5-9 mm	0.56	(0.20, 1.59)	0.274
	≥10 mm	1.00	Reference
Extrahepatic*	R1, <1 mm	2.25	(0.80, 6.33)	0.126
(n = 79)	1-4 mm	3.44	(1.45, 8.18)	0.005
(n = 79)	5-9 mm	1.36	(0.67, 4.08)	0.276
	≥10 mm	1.00	Reference

^†Reference category is ‘no recurrence’ (n = 67). Unknown recurrence pattern in n = 4 patients. *Extrahepatic: recurrence outside the liver with or without hepatic involvement. RM, resection margins; OR, odds ratio; CI, confidence interval.

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