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Table 2 Global recurrence and local recurrence (LR) following n = 242 primary resections for colorectal liver metastases according to resection margins (RMs)

From: Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival

  Resection margins
Recurrence A (R1) n (%) B (1-4 mm) n (%) C (5-9 mm) n (%) D (≥10 mm) n (%) All n (%)
LR only 7 (14.6) 3 (3.9) 3 (6.5) 1 (1.3) 14 (5.8)
LR and hepatic 3 (6.3) 3 (3.9) 3 (6.5) 1 (1.3) 10 (4.1)
LR and extrahepatic 6 (12.5) 10 (13.0) 0 (0.0) 0 (0.0) 16 (6.6)
LR (total)1 16 (33.3) 16 (20.7) 6 (13.0) 2 (2.8) 40 (16.5)
Hepatic only 8 (16.7) 15 (19.5) 7 (15.2) 22 (31.0) 52 (21.5)
Extrahepatic 13 (27.1) 31 (40.3) 17 (37.0) 18 (25.4) 79 (32.6)
Unknown 2 (4.2) 1 (1.3) 0 (0.0) 1 (1.3) 4 (1.7)
Global2 39 (81.3) 63 (81.8) 30 (65.2) 43 (60.5) 175 (72.3)
No recurrence 9 (18.8) 14 (18.2) 16 (34.8) 28 (39.4) 67 (27.7)
Total 48 (100) 77 (100) 46 (100) 71 (100) 242 (100)
  1. Extrahepatic recurrence: recurrence outside the liver with or without hepatic involvement. Statistics: P = 0.0003 (χ2 two-sided exact test) when all groups were included.
  2. 1LR (total): the sum of ‘LR only’, ‘LR and hepatic’ and ‘LR and extrahepatic’.
  3. 2Global recurrence: the sum of ‘LR (total)’, ‘hepatic only’, ‘extrahepatic’, and ‘unknown recurrence’.