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Table 2 Global recurrence and local recurrence (LR) following n = 242 primary resections for colorectal liver metastases according to resection margins (RMs)

From: Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival

 

Resection margins

Recurrence

A (R1) n (%)

B (1-4 mm) n (%)

C (5-9 mm) n (%)

D (≥10 mm) n (%)

All n (%)

LR only

7 (14.6)

3 (3.9)

3 (6.5)

1 (1.3)

14 (5.8)

LR and hepatic

3 (6.3)

3 (3.9)

3 (6.5)

1 (1.3)

10 (4.1)

LR and extrahepatic

6 (12.5)

10 (13.0)

0 (0.0)

0 (0.0)

16 (6.6)

LR (total)1

16 (33.3)

16 (20.7)

6 (13.0)

2 (2.8)

40 (16.5)

Hepatic only

8 (16.7)

15 (19.5)

7 (15.2)

22 (31.0)

52 (21.5)

Extrahepatic

13 (27.1)

31 (40.3)

17 (37.0)

18 (25.4)

79 (32.6)

Unknown

2 (4.2)

1 (1.3)

0 (0.0)

1 (1.3)

4 (1.7)

Global2

39 (81.3)

63 (81.8)

30 (65.2)

43 (60.5)

175 (72.3)

No recurrence

9 (18.8)

14 (18.2)

16 (34.8)

28 (39.4)

67 (27.7)

Total

48 (100)

77 (100)

46 (100)

71 (100)

242 (100)

  1. Extrahepatic recurrence: recurrence outside the liver with or without hepatic involvement. Statistics: P = 0.0003 (χ2 two-sided exact test) when all groups were included.
  2. 1LR (total): the sum of ‘LR only’, ‘LR and hepatic’ and ‘LR and extrahepatic’.
  3. 2Global recurrence: the sum of ‘LR (total)’, ‘hepatic only’, ‘extrahepatic’, and ‘unknown recurrence’.