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Table 2 Results of univariate analyses of disease-free survival (DFS) and overall survival (OS) time

From: Clinicopathological significance of cancer stem cells marked by CD133 and KAI1/CD82 expression in laryngeal squamous cell carcinoma

Variable n Mean DFS P-value Mean OS P-value
(months) (months)
CD133    < 0.001   < 0.001
+ 41 42.4 ± 18.2   37.1 ± 17.7  
- 42 73.3 ± 16.7   65.6 ± 15.4  
KAI1/CD82    < 0.001   < 0.001
+ 34 76.0 ± 19.3   68.0 ± 17.5  
- 49 45.5 ± 16.8   40.1 ± 16.7  
Gender    0.035   0.067
Male 75 56.4 ± 23.0   50.0 ± 21.9  
Female 8 73.1 ± 21.9   65.6 ± 17.0  
Age    0.854   0.280
< 60 27 58.2 ± 21.5   50.9 ± 19.5  
≥ 60 56 57.9 ± 24.3   51.8 ± 23.0  
Location    0.004   0.065
Supraglottic 51 60.3 ± 24.1   53.9 ± 22.5  
Glottic 29 56.4 ± 21.8   49.6 ± 20.5  
Subglottic 3 35.0 ± 13.7   29.3 ± 11.2  
Diameter of tumor    0.015   0.217
< 2.0 cm 43 65.5 ± 19.5   58.5 ± 18.5  
≥ 2.0 cm 40 50.0 ± 24.6   44.0 ± 22.9  
Smoking    0.122   0.132
No 31 62.0 ± 26.4   55.3 ± 22.4  
Yes 52 55.6 ± 21.2   49.3 ± 20.1  
Alcohol    0.365   0.163
No 33 62.4 ± 24.1   54.9 ± 22.5  
Yes 50 55.1 ± 22.6   49.2 ± 21.3  
Grade of tumor    < 0.001   0.009
Well-differentiated 30 71.7 ± 18.7   64.4 ± 17.6  
Moderately-differentiated 47 50.4 ± 22.1   44.5 ± 20.7  
Poorly-differentiated 6 49.3 ± 25.3   42.2 ± 22.8  
Lymph node metastasis    < 0.001   0.003
No 49 67.6 ± 18.9   60.5 ± 17.4  
Yes 34 44.2 ± 22.4   38.6 ± 21.3  
pTNM    < 0.001   < 0.001
I and II 53 68.3 ± 19.2   61.3 ± 17.4  
III and IV 30 40.0 ± 18.4   34.3 ± 18.0