Table 2 Results of univariate analyses of disease-free survival (DFS) and overall survival (OS) time

CD133

< 0.001

< 0.001

+

41

42.4 ± 18.2

37.1 ± 17.7

-

42

73.3 ± 16.7

65.6 ± 15.4

KAI1/CD82

< 0.001

< 0.001

+

34

76.0 ± 19.3

68.0 ± 17.5

-

49

45.5 ± 16.8

40.1 ± 16.7

Gender

0.035

0.067

Male

75

56.4 ± 23.0

50.0 ± 21.9

Female

8

73.1 ± 21.9

65.6 ± 17.0

Age

0.854

0.280

< 60

27

58.2 ± 21.5

50.9 ± 19.5

≥ 60

56

57.9 ± 24.3

51.8 ± 23.0

Location

0.004

0.065

Supraglottic

51

60.3 ± 24.1

53.9 ± 22.5

Glottic

29

56.4 ± 21.8

49.6 ± 20.5

Subglottic

3

35.0 ± 13.7

29.3 ± 11.2

Diameter of tumor

0.015

0.217

< 2.0 cm

43

65.5 ± 19.5

58.5 ± 18.5

≥ 2.0 cm

40

50.0 ± 24.6

44.0 ± 22.9

Smoking

0.122

0.132

No

31

62.0 ± 26.4

55.3 ± 22.4

Yes

52

55.6 ± 21.2

49.3 ± 20.1

Alcohol

0.365

0.163

No

33

62.4 ± 24.1

54.9 ± 22.5

Yes

50

55.1 ± 22.6

49.2 ± 21.3

Grade of tumor

< 0.001

0.009

Well-differentiated

30

71.7 ± 18.7

64.4 ± 17.6

Moderately-differentiated

47

50.4 ± 22.1

44.5 ± 20.7

Poorly-differentiated

6

49.3 ± 25.3

42.2 ± 22.8

Lymph node metastasis

< 0.001

0.003

No

49

67.6 ± 18.9

60.5 ± 17.4

Yes

34

44.2 ± 22.4

38.6 ± 21.3

pTNM

< 0.001

< 0.001

I and II

53

68.3 ± 19.2

61.3 ± 17.4

III and IV

30

40.0 ± 18.4

34.3 ± 18.0