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Table 2 Summary of World Health Organization (WHO) classification of soft tissue tumors of the neck

From: Giant cell angiofibroma misdiagnosed as a vascular malformation and treated with absolute alcohol for one year: a case report and review of the literature

Histologic type Benign Intermediate, locally aggressive Intermediate, rarely metastasizing Malignant
Adipocytic Lipoma and its variants (lipoblastoma, hibernoma, lipomatosis) Atypical lipomatous tumor, well-differentiated liposarcoma Liposarcoma
Fibroblastic/myofibroblastic Fibromatosis colli, myofibroma, giant cell angiofibroma Desmoid-type fibromatosis Solitary fibrous tumor hemangio-pericytoma, inflammatory myofibroblastic tumor (inflammatory pseudotumor) Fibrosarcoma
So-called fibrohistiocytic Benign fibrous histiocytoma, diffuse-type giant cell tumor (pigmented villonodular synovitis) Giant cell tumor of soft tissues Malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma)
Skeletal muscle Rhabdomyoma Rhabdomyosarcoma
Smooth muscle Leiomyoma, angioleiomyoma Leiomyosarcoma
Vascular Hemangioma, lymphangioma Kaposiform hemangioendothelioma Kaposi sarcoma Angiosarcoma
Perivascular Glomus tumor, myopericytoma Malignant glomus tumor
Chondro-osseous Soft tissue chondroma Mesenchymal chondrosarcoma, extraskeletal osteosarcoma
Uncertain differentiation Myxoma Ossifying fibro-myxoid tumor Synovial sarcoma, alveolar soft part sarcoma, primitive neuroectodermal tumor, Ewing sarcoma
  1. Source- Reference [19].