Differences in risk factors between patterns of recurrence in patients after curative resection for advanced gastric carcinoma

Table 3 Univariate and multivariate analyses of recurrence-free survival for hematogenous metastasis

Variables	n	Cumulative recurrence rate at 5-year (%)	Univariate P	Multivariate P relative risk (95% confidence interval)
Age (years)			0.309
<70	74	27.1
≥70	58	13.5
Sex			0.505
Male	87	20.2
Female	45	28.3
Lymphadenectomy			0.234
<D2	61	20.9
D2	71	25.1
Histological differentiation			0.094
G1 or G2	72	14.5
G3 or G4	59	31.2
Depth of tumor invasion			0.009	0.708
pT2 or pT3	64	13.0		1
pT4	68	33.1		1.23 (0.43 to 4.08)
Number of lymph node metastases			<0.001	<0.001
pN0 or pN1	74	2.0		1
pN2 or pN3	58	47.7		26.21 (3.66 to 581.73)
Lymphatic invasion			0.004	0.982
Negative	45	3.3		1
Positive	87	32.5		1.03 (0.14 to 22.26)
Venous invasion			<0.001	0.001
Negative	84	12.9		1
Positive	48	49.3		5.09 (1.89 to 14.87)

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