Lymphoepithelioma-like hepatocellular carcinoma: a case report and a review of the literature

Table 1 Clinicopathological features of lymphoepithelioma-like hepatocellular carcinoma reported in the literature

Case (ref.)	Age (year)s/sex	Tumor location	Number of tumors	Tumor size (mm)	Metastasis at surgery	Preoperative therapy	Surgery	Postoperative therapy	HBV	HCV	LC	EBV	Lymphocyte phenotype dominancy	Survival after surgery
1 [9]	50/M	Not described	1	40	None	None	Liver transplantation	None	+	+	+	-	T cells	Alive without recurrence 10 years
2 [9]	54/M	Not described	2	20	None	Chemo-embolization	Liver transplantation	None	-	-	-	-		Dead of disease 7.7 years
3 [9]	59/M	Not described	4	50	None	None	Liver transplantation	Adjuvant chemotherapy	+	+	+	-		Alive without recurrence 8 years
4 [9]	45/M	Not described	1	20	None	None	Liver transplantation	Adjuvant chemotherapy	-	+	+	-		Alive without recurrence 4.7 years
5 [9]	64/M	Not described	2	40	None	Chemo-embolization	Liver transplantation	Adjuvant chemotherapy	-	-	+	-		Alive without recurrence 3 years
6 [10]	39/F	Not described	1	10	None	None	Liver transplantation	None	-	+	+	+	T cells	Dead of recurrence 5 months
7 [11]	56/M	Right lobe	1	30	None	None	Resection	Chemotherapy for recurrence	-	+	+	-	Not described	Dead of recurrence 21 months
8 [12]	47/F	Adjacent to gall bladder	1	22	None	None	Resection	Not described	-	-	-	-	T cells	Alive without recurrence 15 months
9 [13]	57/M	Hepatic dome	1	27	None	None	Resection	Not described	+	-	+	-	T cells	Alive without recurrence 50 months
10 (present case)	79/M	Lateral segment	1	50	Swollen para-aortic lymph node	None	Resection	Chemotherapy for recurrence	-	-	-	-	T cells	Alive with recurrence (para-aortic lymph nodes) 20 months

HBV: hepatitis B virus, HCV: hepatitis C virus, LC: liver cirrhosis, EBV: Epstein-Barr virus.

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