Table 2 Toxicities related to the study treatment
Toxicity | Grade | Total | |||
|---|---|---|---|---|---|
| Â | 1 | 2 | 3 | 4 | Â |
Hematological | Â | Â | Â | Â | Â |
 Leukopenia | 3 | 2 | 0 | 0 | 5/11 (45%) |
 Neutropenia | 2 | 2 | 1 | 0 | 5/11 (45%) |
 Anemia | 2 | 0 | 0 | 0 | 2/11 (18%) |
 Thrombocytopenia | 2 | 1 | 0 | 0 | 3/11 (27%) |
Biochemical | Â | Â | Â | Â | Â |
 Increased ALT | 6 | 0 | 0 | 0 | 6/11 (55%) |
Non-hematological | Â | Â | Â | Â | Â |
 Rash | 4 | 3 | 0 | 0 | 7/11 (64%) |
 Dry skin | 4 | 2 | 0 | 0 | 6/11 (55%) |
 Pruritus | 3 | 0 | 0 | 0 | 3/11 (27%) |
 Alopecia | 6 | 2 | 0 | 0 | 8/11 (73%) |
 Mucositis | 2 | 0 | 0 | 0 | 2/11 (18%) |
 Fatigue | 5 | 2 | 0 | 0 | 7/11 (64%) |
 Anorexia | 7 | 0 | 0 | 0 | 7/11 (64%) |
 Pyrexia | 0 | 0 | 0 | 0 | 0/11 (0%) |
 Weight loss | 0 | 0 | 0 | 0 | 0/11 (0%) |
 Nausea | 9 | 0 | 0 | 0 | 9/11 (82%) |
 Vomiting | 2 | 1 | 0 | 0 | 3/11 (27%) |
 Diarrhea | 2 | 0 | 0 | 0 | 2/11 (18%) |
 Constipation | 5 | 0 | 0 | 0 | 5/11 (45%) |