Surgical decompression improves recovery from neurological deficit and may provide a survival benefit in patients with diffuse large B-cell lymphoma-associated spinal cord compression: a case-series study

Table 1 Characteristics of patients with diffuse large B-cell lymphoma-associated spinal cord compression

Patient	Sex	Age (years)	Stage	Location	Initial S/S	S/S to Tx (days)	PS (ECOG)	LDH (IU/l)	Extra-nodal involvement >1 site	ASIA scale		IPI	Initial management	NR	DR
Patient	Sex	Age (years)	Stage	Location	Initial S/S	S/S to Tx (days)	PS (ECOG)	LDH (IU/l)	Extra-nodal involvement >1 site	Pre Tx	Post Tx	IPI	Initial management	NR	DR
Surgical group ( n = 6)
1	F	75	1	L	Back pain	3	1	236	No	D	E	Low	DS	CR	CR
2	M	33	1	T	Paraplegia	1	2	381	No	A	E	L-I	DS	CR	CR
3	F	44	4	T	Paraplegia	2	2	437	No	A	E	H-I	DS	CR	CR
4	F	22	4	T	Urine retention	1	2	310	Yes	C	E	H-I	DS	CR	CR
5	F	40	4	T	Low limb weakness	7	2	253	Yes	C	E	High	DS	CR	PR
6	F	58	1	L	Low limb weakness	7	1	188	No	C	E	Low	DS	CR	CR
Nonsurgical group ( n = 5)
7	M	63	1	T	Back pain	4	2	237	No	C	D	L-I	CT	PR	CR
8	F	53	4	L, S	Low limb weakness	16	3	381	Yes	B	D	H-I	RT	PR	CR
9	F	73	4	T, L	Urine retention	1	3	1,021	Yes	A	E	High	CT	CR	PR
10	F	54	4	S	Low limb weakness	3	2	223	Yes	B	D	H-I	CT	PR	PR
11	M	53	4	T, S	Back pain	30	3	304	Yes	A	B	High	CT	PR	PR

M, male; F, female; T, thoracic spine; L, lumbar spine; S, sacral spine; S/S, symptoms and signs; Tx, treatment; PS, performance status; ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase; ASIA, American Spinal Injury Association; IPI, International Prognostic Index; L-I, low-intermediate; H-I, high-intermediate DS, decompression surgery; CT, chemotherapy; RT, radiotherapy; NR, neurological response; CR, complete response; PR, partial response; DR, disease response.

ISSN: 1477-7819