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Table 3 Immunohistochemical findings of 13 cases of pulmonary SH

From: Pulmonary sclerosing hemangioma: a unique epithelial neoplasm of the lung (report of 26 cases)

Markers

Antibodies

Cases examined ( n)

Lining cells (na, %b)

Round cells (na, %b)

Epithelial markers

EMA

12

12 (100.00%)

12 (100.00%)

 

PCK

7

7 (100.00%)

0 (0.00%)

 

CK

5

5 (100.00%)

0 (0.00%)

 

CK-7

8

8 (100.00%)

2 (25.00%)

 

TTF-1

10

10 (100.00%)

10 (100.00%)

Neuroendocrine markers

Syn

7

0 (0.00%)

0 (0.00%)

 

CgA

6

0 (0.00%)

0 (0.00%)

 

S-100

6

0 (0.00%)

0 (0.00%)

 

NSE

3

0 (0.00%)

0 (0.00%)

Vascular-endothelial markers

CD34

3

1 (33.33%)

0 (0.00%)

Myoepithelial markers

Desmin

1

0 (0.00%)

0 (0.00%)

Proliferation markers

Ki-67

4

0 (0.00%)

4 (100.00%)c

  1. aNumber of cases revealing positive results.
  2. bProportion of positive cases to the whole examined ones.
  3. cThe expression of Ki-67 in all positive cases was <5%.