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Table 5 Univariate and multivariate predictors of disease-free survival (DFS)

From: A retrospective study: platinum-based induction chemotherapy combined with gemcitabine or paclitaxel for stage IIB-IIIA central non-small-cell lung cancer

Variable

Subset

HR

95% CI

P-value

Univariate analysis

    

 age

>60

   
 

≤60

0.845

0.425 to1.680

0.632

 sex

male

   
 

female

2.133

0.954 to4.769

0.065

 histological type

squamous

   
 

nonsquamous

2.191

1.088 to4.409

0.028

 induction regimen

gemcitabine

   
 

paclitaxel

0.466

0.227 to0.957

0.038

 T size before chemotherapy

>5cm

   
 

≤5cm

0.645

0.289 to1.440

0.285

 cN2

(+)

   
 

(-)

0.186

0.073 to0.474

0.0004

 clinical response

CR/PR

   
 

SD/PD

0.654

0.329 to1.301

0.226

 type of resection

lobectomy

   
 

pneumonectomy

1.403

0.576 to3.419

0.456

 T size after chemotherapy

>3cm

   
 

≤3cm

0.561

0.245 to 1.287

0.173

 pN status

N2

   
 

N0/N1

1.249

0.833 to1.873

0.283

 pN status

N0

   
 

N1/N2

1.647

0.804 to3.373

0.172

Multivariate analysis

    

 cN2

(+)

   
 

(-)

0.179

0.060 to0.531

0.002

 clinical response

CR/PR

   
 

SD/PD

0.295

0.114 to0.766

0.012