Figure 1

(A) DACT2 mRNA expression in 30 pairs of clinical samples. The expression level of DACT2 mRNA was quantitatively determined by RT-PCR for tumor tissue specimens and its corresponding nontumor tissue specimens. The mean expression level of DACT2 in each group was indicated (*P < 0.05, Student’s t- test). Representative immunohistochemical staining of DACT2 protein in liver cirrhosis tissue (B) and hepatocellular carcinoma section (C) and low expression of DACT2 in tumor at the tumor-normal interface (D) (original magnification, ×10).