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Table 3 Independent risk predictors for diagnosis of thyroid malignancy under multivariate logistic regression analysis (n = 1,789 patients)

From: Hashimoto’s Thyroiditis, microcalcification and raised thyrotropin levels within normal range are associated with thyroid cancer

Variable

Adjusted odds ratio

95% CI

P-value

Age, yr

  

0.004*

0 ~ 14

1.00

  

15~29

1.217

0.164, 9.032

0.848

30~44

1.544

0.215, 11.092

0.666

45~59

1.188

0.165, 8.550

0.864

60~74

0.724

0.098, 5.321

0.751

75~89

2.852

0.300, 27.138

0.362

TSH, mIU/La

  

0.001*

<0.35

1.00

  

0.35 to 1.17

1.079

0.663, 1.756

0.759

1.18 to 1.96

1.357

0.835, 2.207

0.218

1.97 to 4.94

1.951

1.201, 3.171

0.007*

>4.94

1.235

0.598, 2.550

0.568

HT

   

Absent

1.00

  

Present

3.732

2.563, 5.435

<0.001*

Calcification

   

Coarsecalcifications

1.00

  

Microcalcification

14.486

11.374, 18.449

<0.001*

  1. aPatients with free T3 (fT3), fT4, or TSH measurements within the normal range were divided into tertiles of similar size, respectively. Variables assigned odds ratios of 1.0 were used as the reference for multivariate analysis. *Statistically significant (P <0.05).