Table 1 Clinicopathological characteristics
Young (age ≤40 years) | Old (age >40 years) | P | |
|---|---|---|---|
n = 31 | n = 780 | ||
Epidemiology | |||
Sex: Male/Female | 24/7 (77%/23%) | 644/136 (83%/17%) | NS |
HBs-Ag positive | 26 (84%) | 321 (41%) | <0.0001 |
HCV-Ab positive | 1 (3%) | 310 (40%) | <0.0001 |
Biochemical Factors | |||
Albumin ≥4.0 g/l | 17 (55%) | 411 (53%) | NS |
Total bilirubin ≥0.8 mg/dl | 17 (55%) | 379 (49%) | NS |
ICGR15 ≥15 | 3 (10%) | 360 (46%) | 0.0001 |
AFP ≥200 ng/ml | 16 (52%) | 210 (27%) | 0.0026 |
Tumor Factors | |||
Number of tumors: 1 | 20 (65%) | 522 (67%) | NS |
2 to 3 | 6 (19%) | 183 (23%) | |
≥4 | 5 (16%) | 75 (10%) | |
Maximum size of tumors: <2 cm | 4 (12%) | 83 (11%) | 0.0074 |
≥2 cm, <5 cm | 7 (23%) | 395 (50%) | |
≥5 cm | 20 (65%) | 303 (39%) | |
Macroscopic classification: simple nodular type | 10 (32%) | 408 (52%) | NS |
simple nodular type with extranodular grow | 10 (32%) | 222 (28%) | |
confluent multinodular type | 8 (26%) | 122 (16%) | |
infiltrative type | 0 (0%) | 6 (1%) | |
others | 3 (10%) | 22 (3%) | |
Distant metastasis positive | 2 (6%) | 18 (2%) | NS |
Surgical Factors | |||
Anatomical resection | 29 (94%) | 525 (67%) | 0.0021 |
Histological Factors | |||
Differentiation: well | 3 (10%) | 114 (15%) | NS |
moderate | 13 (42%) | 430 (55%) | |
poor | 14 (45%) | 209 (27%) | |
others | 1 (3%) | 27 (3%) | |
vp:vp0 | 14 (45%) | 569 (73%) | 0.0026 |
vp1 | 9 (29%) | 125 (16%) | |
vp2,3,4 | 8 (26%) | 86 (11%) | |
im | 16 (52%) | 264 (34%) | 0.0413 |
cirrhosis | 9 (29%) | 287 (37%) | NS |