Table 1 Clinicopathologic features and surgical treatments of patients with large hepatocellular carcinoma
From: The effect of alkaline phosphatase and intrahepatic metastases in large hepatocellular carcinoma
Gender | |
|---|---|
Male | 80 (87.9%) |
Female | 11 (12.1%) |
Age (years) | 52 (19 to 82) |
Etiology | |
HBV | 60 (65.9%) |
HCV | 2 (2.2%) |
Alcohol | 4 (4.4%) |
non-B, non-C | 21 (23.1%) |
Others | 3 (3.3%) |
AFP (ng/dL) | |
< 1000 | 58 (63.7%) |
≥ 1000 | 33 (36.3%) |
PIVKA-II (mAU/mL) | |
< 200 | 28 (30.8%) |
≥ 200 | 63 (69.2%) |
White blood cells (/uL) | 6,040 (2,100 to 10,790) |
Hemoglobin (g/dL) | 14.2 (8.1 to 17.0) |
Platelet counts (/uL) | 205,000 (61,000 to 627,000) |
INR | 1.07 (0.91 to 1.31) |
Albumin (g/dL) | 4.0 (2.9 to 5.0) |
Total bilirubin (mg/dL) | 0.7 (0.3 to 1.2) |
AST (U/L) | 43 (14 to 353) |
ALT (U/L) | 39 (12 to 385) |
ALP (U/L) | 92 (38 to 287) |
Creatinine (mg/dL) | 0.89 (0.65 to 2.99) |
Maximum tumor size (cm) | 12.3 (10 to 21) |
Cirrhosis | 17 (18.7%) |
Grade | |
1 and 2 | 75 (82.4%) |
3 and 4 | 16 (17.6%) |
Capsular invasion | 77 (84.6%) |
Microvascular invasion | 85 (93.4%) |
Portal vein invasion | 19 (20.9%) |
Bile duct invasion | 4 (4.4%) |
Serosa involvement | 8 (8.8%) |
Intrahepatic metastasis | 30 (33.0%) |
Multicentric occurrence | 5 (5.5%) |