Table 2 Kaplan-Meier analysis of 5-year disease-free and melanoma-specific survival
Clinical and pathological factors | Disease-free survival | Melanoma-specific survival |
|---|---|---|
Age (years) | Â | Â |
≤50 | 45.3 | 64.1 |
>50 | 28.9 | 52.2 |
P value | 0.0098 | 0.03 |
Method of diagnosis | Â | Â |
Sentinel lymph node biopsy | 41.3 | 69.3 |
Clinical | 29.2 | 43.7 |
P value | 0.4 | 0.004 |
Primary site | Â | Â |
Trunk | 22.6 | 45.2 |
Lower extremity | 41.5 | 62.7 |
Unknown | 37.5 | 50 |
P value | 0.1 | 0.5 |
T stage | Â | Â |
T1 to T2 | 52.9 | 73.5 |
T3 | 27.8 | 47.2 |
T4 | 41.5 | 65.8 |
P value | 0.2 | 0.4 |
Ulceration | Â | Â |
No | 36.8 | 58.6 |
Yes | 29.3 | 54.4 |
P value | 0.6 | 0.2 |
Number of positive lymph nodes | Â | Â |
1 (N1) | 41.7 | 65.5 |
2 or 3 (N2) | 36.4 | 54.5 |
≥4 (N3) | 7.1 | 14.3 |
P value | 0.007 | 0.0009 |
Extent of nodal involvement | Â | Â |
Superficial | 34.9 | 55.6 |
Superficial + deep | 19.05 | 33.3 |
P value | 0.001 | 0.001 |