Skip to main content

Table 1 Clinicopathologic characteristics of ILC in this study

From: EZH2 expression in invasive lobular carcinoma of the breast

   EZH2 expression N(%) P
  Total N(%) 0% to 5% 5% to 25% 25% to 50% >50%  
Age at diagnosis       0.255
  <50 28 (57.1) 3 (37.5) 6 (75.0) 2 (33.3) 17 (63.0)  
  ≤50 21 (42.9) 5 (62.5) 2 (25.0) 4 (66.7) 10 (37.0)  
Menstrual status       0.472
  Premenopausal 27 (55.1) 4 (50.0) 6 (75.0) 2 (33.3) 15 (55.6)  
  Postmenopausal 22 (44.9) 4 (50.0) 2 (25.0) 4 (66.7) 12 (44.4)  
Body mass index       0.647
  Underweight (<20) 3 (6.1) 1 (12.5) 0 (0) 1 (16.7) 1 (3.7)  
  Normal (≥20, <25) 29 (59.2) 4 (50.0) 6 (75.0) 2 (33.3) 17 (63.0)  
  Overweight (≥25) 17 (34.7) 3 (37.5) 2 (25.0) 3 (50.0) 9 (33.3)  
Side of primary tumor       0.587
  Left 25 (51.0) 5 (62.5) 4 (50.0) 4 (66.7) 12 (44.4)  
  Right 21 (42.9) 3 (37.5) 3 (37.5) 1 (16.7) 14 (51.9)  
  Bilateral 3 (6.1) 0 (0) 1 (12.5) 1 (16.7) 1 (3.7)  
Multifocality       0.981
  Monofocal 38 (77.6) 6 (75.0) 6 (75.0) 5 (83.3) 21 (77.8)  
  Multifocal 11 (22.4) 2 (25.0) 2 (25.0) 1 (16.7) 6 (22.2)  
T stage       0.770
  T1 22 (44.9) 4 (50.0) 5 (62.5) 2 (33.3) 11 (40.7)  
  T2 23 (46.9) 3 (37.5) 3 (37.5) 4 (66.7) 13 (48.1)  
  T3 4 (8.2) 1 (12.5) 0 (0) 0 (0) 3 (11.1)  
Lymph node metastasis       0.403
  N0 28 (57.1) 6 (75.0) 6 (75.0) 4 (66.7) 12 (44.4)  
  N1 8 (16.3) 1 (12.5) 2 (25.0) 0 (0) 5 (18.5)  
  N2 4 (8.2) 1 (12.5) 0 (0) 0 (0) 3 (11.1)  
  N3 9 (18.4) 0 (0) 0 (0) 2 (33.3) 7 (25.9)  
Nuclear grade       0.025
  1 7 (14.3) 4 (50.0) 2 (25.0) 0 (0) 1 (3.7)  
  2 32 (65.3) 4 (50.0) 5 (62.5) 5 (83.3) 18 (66.7)  
  3 10 (20.4) 0 (0) 1 (12.5) 1 (16.7) 8 (29.6)  
Estrogen receptor status       0.629
  Negative 13 (26.5) 1 (12.5) 3 (37.5) 1 (16.7) 8 (29.6)  
  Positive 36 (73.5) 7 (87.5) 5 (62.5) 5 (83.3) 19 (70.4)  
Progesterone receptor status       0.615
  Negative 10 (20.4) 2 (25.0) 2 (25.0) 0 (0) 6 (22.2)  
  Positive 39 (79.6) 6 (75.0) 6 (75.0) 6 (100.0) 21 (77.8)  
Cerb-B2 status       0.410
  Negative 39 (79.6) 5 (62.5) 7 (87.5) 4 (66.7) 23 (85.2)  
  Positive 10 (20.4) 3 (37.5) 1 (12.5) 2 (33.3) 4 (14.8)  
p53       0.093
  Negative 37 (75.5) 4 (50.0) 5 (62.5) 4 (66.7) 24 (88.9)  
  Positive 12 (24.5) 4 (50.0) 3 (37.5) 2 (33.3) 3 (11.1)