Table 3 Results of Glut-1, HIF-1α, PI3K, and p-Akt and outcome in 12 inflammatory myofibroblastic tumors of head and neck
From: Expression of hypoxia-related markers in inflammatory myofibroblastic tumors of the head and neck
Case | Site | Recurrence | Metastasis | Follow-up | Expression of | |||
|---|---|---|---|---|---|---|---|---|
Glut-1 | HIF-1α | PI3K | p-Akt | |||||
1 | Larynx | No | No | No evidence of disease (68 months) | − | + | − | − |
2 | Tonsil | No | No | No evidence of disease (84 months) | + | − | − | − |
3 | Maxillare | Yes | No | No evidence of disease (88 months after first surgery) | − | − | − | + |
4 | Tongue | No | No | No evidence of disease (41 months) | − | − | − | − |
5 | Tonsil | No | No | No evidence of disease (23 months) | − | − | − | − |
6 | Hypopharynx | Yes | No | No evidence of disease (47 months after first surgery) | − | + | + | + |
7 | Maxillary sinus | Yes | Metastasis to cervical lymph node | Died of disease (13 months after initial treatment) | + | + | + | + |
8 | Mouth floor | No | No | No evidence of disease (132 months) | − | − | − | − |
9 | Maxillary sinus | Yes | Metastasis to cervical lymph node | Died of disease (11 months after first treatment) | + | + | + | + |
10 | Maxillary sinus | Yes | No | No evidence of disease (70 months after first treatment) | + | + | − | − |
11 | Maxillary sinus | Yes | No | Died of disease (35 months after initial treatment) | + | + | + | + |
12 | Neck | No | No | No evidence of disease (13 months) | − | − | − | − |