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Table 1 Clinical characteristics of patients with gastric cancer receiving adjuvant TS-1 and 5-fluorouracil chemotherapy

From: Total gastrectomy increases the incidence of grade III and IV toxicities in patients with gastric cancer receiving adjuvant TS-1 treatment

 

TS-1 adjuvant group, n (%)

5-fluorouracil adjuvant group, n (%)

p value

Total

40 (100)

193 (100)

 

Male gender

24 (60)

123 (63.7)

0.39

Median age (range)

61.0 (27 to 88)

61.1 (27 to 90)

0.63

ECOG performance status scale

   

 0

32 (80)

133 (68.9)

0.24

 1

7 (17.5)

47 (24.4)

 

 2

1 (2.5)

13 (6.7)

 

Histological type

   

 Intestinal

15 (37.5)

61 (31.6)

0.29

 Diffuse

25 (62.5)

132 (68.4)

 

Gastrectomy method

   

 Subtotal

25 (62.5)

124 (64.2)

0.48

 Total

15 (37.5)

69 (35.8)

 

TNM stage (AJCC, 6 th )

   

 Ib

5 (12.5)

48 (24.9)

0.12

 II

17 (42.5)

46 (23.8)

 

 IIIa

8 (20)

51 (26.4)

 

 IIIb

2 (5)

13 (6.7)

 

 IV

8 (20)

35 (18.1)

 

Tumor stage (AJCC, 6 th )

  

0.14

 T1

6 (15)

45 (23.3)

 

 T2

22 (55)

68 (35.2)

 

 T3

9 (22.5)

59 (30.6)

 

 T4

3 (7.5)

21 (10.9)

 

Nodal stage (AJCC, 6 th )

   

 N0

2 (5)

28 (14.5)

0.28

 N1

23 (57.5)

97 (50.3)

 

 N2

9 (22.5)

50 (25.9)

 

 N3

6 (15)

18 (9.3)

 
  1. AJCC, American Joint Committee on Cancer; ECOG, Eastern Cooperative Oncology Group; TNM, Tumor-node-metastasis.