Table 3 Univariate and multivariate analysis of factors associated with survival

Group 1 (AA + GBM)

Age (per year)

1.023

1.014–1.033

<0.0001

1.023

1.013–1.034

<0.0001

Gender (female versus male)

1.023

1.014–1.033

<0.0001

0.810

0.590–1.112

0.1928

Resection (total resection versus non-total resection)

1.348

0.987–1.840

0.06

1.994

1.440–2.763

<0.0001

IDH1 (mutation versus wild-type)

0.427

0.253–0.719

0.0014

0.708

0.403–1.243

0.2290

MGMT (methylation versus unmethylation)

0.671

0.494–0.911

0.0106

0.614

0.442–0.852

0.0035

Histology (AA versus GBM)

0.372

0.242–0.571

<0.0001

0.419

0.264–0.666

0.0002

Group 2 (AO + AOA)

Age (per year)

1.025

0.971–1.083

0.3672

1.094

1.003–1.193

0.0421

Gender (female versus male)

0.499

0.145–1.717

0.2703

0.156

0.027–0.890

0.0365

Resection (total resection versus non-total resection)

0.886

0.289–3.031

0.037

0.852

0.178–4.074

0.8412

IDH1 (mutation versus wild-type)

0.563

0.172–1.848

0.3436

2.271

0.415–12.444

0.3444

MGMT (methylation versus unmethylation)

0.115

0.033–0.402

0.0007

0.041

0.007–0.257

0.0006

1p19q (co-deletion versus non co-deletion)

4.208

1.099–16.114

0.0359

4.720

0.685–32.526

0.1150

Histology (AO versus AOA)

0.723

0.220–2.377

0.5937

1.935

0.383–9.785

0.4247