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Table 1 Patients and characteristics

From: Prognostic value of isocitrate dehydrogenase 1, O6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients

 

Histologic subtype

Characteristic

AO (n = 30)

AOA (n = 26)

AA (n = 40)

GBM (n = 171)

Gender

    

Male/female ratio

0.76

1.36

1.22

1.59

Male, n

13

15

22

105

Female, n

17

11

18

66

Age, years

    

Median

45.0

49.5

45.5

61.0

Range

16 to 77

30 to 65

10 to 72

3 to 81

Karnofsky performance status

    

Median

100

100

90

90

Range

40 to 100

70 to 100

40 to 100

20 to 100

Surgery

    

Total removal, n

22

13

8

74

Partial removal, n

7

12

21

73

Biopsy, n

1

1

11

24

IDH1 mutation, n

20(66.7%)

12(46.2%)

12(30.0%)

12(7.0%)

MGMT promoter methylation, n

24(80.0%)

19(73.1%)

18(45.0%)

73(42.7%)

1p/19q co-deletion, n

18(60.0%)

11(42.3%)

  

Survival, months, median

70.5

80.0

40.0

14.0

  1. AO, anaplastic oligodendroglioma; AOA, anaplastic oligoastrocytoma; AA, anaplastic astrocytoma; GBM, glioblastoma; n, number of patients.