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Table 1 Patients and characteristics

From: Prognostic value of isocitrate dehydrogenase 1, O6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients

  Histologic subtype
Characteristic AO (n = 30) AOA (n = 26) AA (n = 40) GBM (n = 171)
Gender     
Male/female ratio 0.76 1.36 1.22 1.59
Male, n 13 15 22 105
Female, n 17 11 18 66
Age, years     
Median 45.0 49.5 45.5 61.0
Range 16 to 77 30 to 65 10 to 72 3 to 81
Karnofsky performance status     
Median 100 100 90 90
Range 40 to 100 70 to 100 40 to 100 20 to 100
Surgery     
Total removal, n 22 13 8 74
Partial removal, n 7 12 21 73
Biopsy, n 1 1 11 24
IDH1 mutation, n 20(66.7%) 12(46.2%) 12(30.0%) 12(7.0%)
MGMT promoter methylation, n 24(80.0%) 19(73.1%) 18(45.0%) 73(42.7%)
1p/19q co-deletion, n 18(60.0%) 11(42.3%)   
Survival, months, median 70.5 80.0 40.0 14.0
  1. AO, anaplastic oligodendroglioma; AOA, anaplastic oligoastrocytoma; AA, anaplastic astrocytoma; GBM, glioblastoma; n, number of patients.