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Table 1 Date for the 10 cases

From: Osteomyelitis of the femur mimicking bone tumors: a review of 10 cases

Case

Age/sex

Nocturnal pain/BW loss

Delayed diagnosis (month)

Radiography

MRI

Preoperative diagnosis

Underlying disease

Treatment (antibiotics/weeks)

WBC/mm3

ESR (mm/h)/ CRP (mg/L)

Recurrence/pathological fracture/surgery times

culture

1

57/M

+/-

4

Moth-eaten osteolysis

 

Ewing sarcoma

 

S+D+C (36)

10500

132/12.7

+/+/4

Klebsiella pneumoniae

    

Laminated periosteal reaction

        

2

33/M

+/+

6

Moth-eaten osteolysis

 

Ewing sarcoma

Drug abuser

S+D+C+O (40)

19900

Nil/15.4

+/+/4

Klebsiella pneumoniae

    

Laminated periosteal reaction

        

3

54/F

+/-

3

Moth-eaten osteolysis

Cortex destruction Soft tissue mass

Ewing sarcoma

DM

S+D+C+O (9)

10400

Nil/7.29

-/-/1

Klebsiella pneumoniae

    

Laminated periosteal reaction

        

4

37/F

-/-

1

Moth-eaten osteolysis

Cortex destruction

Leukemia

DM

S+D+C+O (4)

16500

91/12.9

-/-/1

Klebsiella pneumoniae

    

Monolayer periosteal reaction

Penumbra sign

       

5

37/M

-/-

8

Moth-eaten osteolysis Laminated periosteal reaction

 

Ewing sarcoma

DM

S+D+C+O (44)

16600

Nil/21.6

+/+/2

Klebsiella pneumoniae

6

14/M

+/ +

4

Osteolysis Laminated periosteal reaction

Extensive soft tissue

Ewing sarcoma

 

Casting (15)

7000

45/0.95

+/+/1

Staphylococcus aureus

7

13/M

-/-

1

Hyperostosis Septated periosteal reaction

Extensive soft tissue

Malignant change of osteomyelitis

DM

S+D+C (4)

12200

68/13

-/-/1

Klebsiella pneumoniae

8

30/M

+/-

4

Osteolysis

Soft tissue mass Cortex destruction

Metastatic lesion

 

S+D+C (6)

11000

58/1.13

-/-/ 1

Staphylococcus aureus

    

Laminated periosteal reaction

        

9

50/F

+/+

5

Osteolysis

Periosteal reaction

  

S+D+C (42)

10800

93/13.7

+/-/2

Staphylococcus aureus

    

Laminated periosteal reaction

        

10

54/F

+/-

3

Hyperostosis

Enhancing lesion

Metastatic tumors

 

S+D+C (4)

8700

NIL/1.15

-/-/1

Propionibacterium

    

Laminated periosteal reaction

        

Summary

 

Night pain: 7

AVG: 3.9

   

DM: 4

AVG: 20.4 weeks

Elevated: 8

Elevated CRP (>0.5 mg/L): 10

Recurrence/fracture: 5/4

 
  

Weight loss: 3

    

Drug abuser: 1

     
  1. BW, body weight; CRP, C-reactive protein; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; MRI, magnetic resonance imaging; S+D+C+O, sequestrectomy + debridement + bone cement + open reduction internal fixation; WBC, white blood cell.