From: Osteomyelitis of the femur mimicking bone tumors: a review of 10 cases
Case | Age/sex | Nocturnal pain/BW loss | Delayed diagnosis (month) | Radiography | MRI | Preoperative diagnosis | Underlying disease | Treatment (antibiotics/weeks) | WBC/mm3 | ESR (mm/h)/ CRP (mg/L) | Recurrence/pathological fracture/surgery times | culture |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 57/M | +/- | 4 | Moth-eaten osteolysis | Â | Ewing sarcoma | Â | S+D+C (36) | 10500 | 132/12.7 | +/+/4 | Klebsiella pneumoniae |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
2 | 33/M | +/+ | 6 | Moth-eaten osteolysis | Â | Ewing sarcoma | Drug abuser | S+D+C+O (40) | 19900 | Nil/15.4 | +/+/4 | Klebsiella pneumoniae |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
3 | 54/F | +/- | 3 | Moth-eaten osteolysis | Cortex destruction Soft tissue mass | Ewing sarcoma | DM | S+D+C+O (9) | 10400 | Nil/7.29 | -/-/1 | Klebsiella pneumoniae |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
4 | 37/F | -/- | 1 | Moth-eaten osteolysis | Cortex destruction | Leukemia | DM | S+D+C+O (4) | 16500 | 91/12.9 | -/-/1 | Klebsiella pneumoniae |
 |  |  |  | Monolayer periosteal reaction | Penumbra sign |  |  |  |  |  |  |  |
5 | 37/M | -/- | 8 | Moth-eaten osteolysis Laminated periosteal reaction | Â | Ewing sarcoma | DM | S+D+C+O (44) | 16600 | Nil/21.6 | +/+/2 | Klebsiella pneumoniae |
6 | 14/M | +/ + | 4 | Osteolysis Laminated periosteal reaction | Extensive soft tissue | Ewing sarcoma | Â | Casting (15) | 7000 | 45/0.95 | +/+/1 | Staphylococcus aureus |
7 | 13/M | -/- | 1 | Hyperostosis Septated periosteal reaction | Extensive soft tissue | Malignant change of osteomyelitis | DM | S+D+C (4) | 12200 | 68/13 | -/-/1 | Klebsiella pneumoniae |
8 | 30/M | +/- | 4 | Osteolysis | Soft tissue mass Cortex destruction | Metastatic lesion | Â | S+D+C (6) | 11000 | 58/1.13 | -/-/ 1 | Staphylococcus aureus |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
9 | 50/F | +/+ | 5 | Osteolysis | Periosteal reaction | Â | Â | S+D+C (42) | 10800 | 93/13.7 | +/-/2 | Staphylococcus aureus |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
10 | 54/F | +/- | 3 | Hyperostosis | Enhancing lesion | Metastatic tumors | Â | S+D+C (4) | 8700 | NIL/1.15 | -/-/1 | Propionibacterium |
 |  |  |  | Laminated periosteal reaction |  |  |  |  |  |  |  |  |
Summary | Â | Night pain: 7 | AVG: 3.9 | Â | Â | Â | DM: 4 | AVG: 20.4 weeks | Elevated: 8 | Elevated CRP (>0.5 mg/L): 10 | Recurrence/fracture: 5/4 | Â |
 |  | Weight loss: 3 |  |  |  |  | Drug abuser: 1 |  |  |  |  |  |