Figure 3
From: Synchronous primary neoplasms of the bladder, skin and breast in a male patient: a case report
Bladder cancer. (A) Low-power photomicrograph showing malignant bladder epithelial proliferation organized in papillary structures, nests, sometimes with central necrosis, solid and cords that diffusely infiltrate subepithelial corium and the muscularis (magnification 4x); (B) High-power photomicrograph showing epithelial cells of medium-great size, with altered nucleus-cytoplasm ratio, leptocromatinic nucleus, nucleolus often prominent and large eosinophilic cytoplasm (magnification 40x); the cells resulted negative to immunohistochemical staining for GCDFP-15 (C), positive for CK7 (D) and negative per CK20 (E) (magnification 40x).