Table 1 Summary of reported cases of primary medulla oblongata germinoma
From: Primary medulla oblongata germinomas: two case reports and review of the literature
Number | Author (year) [reference] | Age, years | Sex | Symptoms | Treatment | Outcome | Follow-up period |
|---|---|---|---|---|---|---|---|
1 | Poungvarin [15] | 17 | M | Pneumonia and presented with intermittent apnea | S, RT | Died of pneumonia | 92 days |
2 | Hashimoto [14] | 19 | M | Klinefelter syndrome, CN IX, X paresis, sleep apnea | Biopsy, WB+WS RT | CR | 2 months |
3 | Sugiyama [12] | 32 | F | CN VII, IX, XI, XII paresis, ataxia | PR, Local+WS RT | CR | 9 years |
4 | Israel (1996) [8] | 40 | F | Headache, vomiting, cerebellar signs | STR, CMT, FB RT | CR | 18 months |
5 | Nakajima [11] | 18 | F | Hiccups, nystagmus | PR, CMT, GKS | CR | 8 months |
6 | Yoshida (2003) [8] | 33 | F | CN V, VI, VII paresis | STR, CMT | CR | 7 months |
7 | Yen [5] | 16 | F | Static and kinetic ataxia | STR, FB+WB+WS RT | CR | 7 years |
8 | Yang (2009)[8] | 12 | M | CN IX, X, XII palsy, lethargy, loss of appetite | PR, CMT, RT | CR | 6 months |
9 | Akimoto [4] | 30 | F | Left CN VI palsy, bilateral palsy of CNs IX, X,XII | TR, CMT, FB RT | CR | 1 year |
10 | Akimoto [4] | 24 | M | Headache | PR, CMT, FB RT | CR | 8 months |
11 | Yasuhara [3] | 27 | F | CN VIII, IX, X,XII paresis, ataxia, sleep apnea, numbness of limbs | Biopsy, CMT, RT | CR | 6 months |
12 | Shuto [2] | 28 | M | Loss of balance | STR, CMT, FB+WS RT | CR | 3 years |
13 | Nakatsuka [8] | 31 | F | Hiccups, hoarseness, and swallowing disturbances | STR, CMT, FB RT | CR | 6 months |
14 | This study | 14 | M | CN VII VIII, IX paresis, nystagmus | STR, GKS, CMT | CR | 4.5 years |
15 | This study | 22 | F | CN IX XI paresis, nystagmus, numbness of limbs | GKS, STR | Died of pneumonia | 8 months |