Figure 1

Representative result of denaturing high performance liquid chromatography and sequencing for EGFR L858R mutations. (A) L858R missense mutations in exon 21 were found using the denaturing high performance liquid chromatography-based method. A single peak on the left (123 bp) indicates mutant alleles, and that on the right indicates wild-type alleles at about 138 bp. (B) No mutations were detected under sequencing conditions.