BMP4, a new prognostic factor for glioma

Table 1 Relationship between BMP4 expression and clinic-pathological factors of 630 gliomas

Variable	n	BMP4 (n(%))		X²	P value
		+	-
Sex				0.517	0.472
Male	347	124(35.73)	223(64.27%)
Female	283	109(38.52)	174(61.48)
Age (years)				2.982	0.099
≤35	307	124(40.39)	183(59.61)
>35	323	109(33.75)	214(66.25)
KPS score				3.208	0.201
10-50	83	38(45.78)	45(54.22)
60-70	135	49(36.30)	86(63.70)
80-100	412	146(35.44)	266(64.56)
Extent of resection				21.702	0.001
Partial	139	28(20.14)	111(79.86)
Total	491	205(41.75)	286(58.25)
Ki67				78.795	0.001
+	291	54(18.56)	237(81.44)
_	339	179(52.80)	160(47.20)
WHO grade				40.996	0.001
II	247	128(51.82)	119(48.18)
III-IV	383	105(27.42)	278(72.58)

+, high BMP4 expression; –, loss/low BMP4 expression. KPS, Karnofsky Performance Status; WHO, World Health Organization.

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