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Table 1 Summary of the described cases of MCC metastatic to the pancreas

From: Metastatic Merkel cell carcinoma (MCC) of pancreas and breast: a unique case

Author

Year

Presentation

Safadi R et al.[8]

1996

A 69-year-old woman with chronic lymphocytic leukemia who developed MCC and obstructive jaundice due to pancreatic metastases of the MCC.

Bachmeyer C et al.[7]

2002

A 57-year-old man with MCC on the left lower eyelid. The patient died of generalized carcinomatosis after metastatic MCC invading the stomach and pancreas.

Ouellette JR et al.[2]

2004

A 64-year-old man with obstructive jaundice approximately two years after having a MCC resected from his finger. He underwent a successful pancreaticoduodenectomy with pathology confirming metastatic MCC.

Adsey et al.[6]

2004

One case from a pool of 38 metastatic tumors of the pancreas. No data about the age and the clinical presentation available.

Bachmann J et al.[5]

2005

An 82-year-old woman presented with an abdominal mass, 2 years prior she had an excision done on her eyebrow that was reported as MCC. Final histopathology of the mass was an endocrine carcinoma in the pancreatic tail consistent with metastatic MCC.

Hizawa K et al.[9]

2007

An 85-year-old woman with MCC on the right eyelid. The patient died of an intra-abdominal metastatic MCC that directly invaded the stomach, pancreas and distal duodenum.

Dim DC et al.[3]

2009

A 79-year-old woman with a large pancreatic tail mass and a history of MCC of the upper extremity.

Krejčí K et al.[10]

2010

A 62-year-old man who developed a MCC in the right gluteal region 8 years after combined kidney-pancreas transplantation. The tumor was generalized and metastasized into the pancreatic graft. The patient died 9 months after diagnosis.

Bernstein J et al.[4]

2012

A 56-year-old male presented with a palpable femoral lymph node of a left posterior thigh nodule. Histopathological examination revealed a MCC. A heterogeneous lesion in the pancreatic tail was identified by endoscopic ultrasound.