Table 2 Correlation between Gli2 expression and clinicopathologic characteristics in HCC

Gender

Male

33

20

0.097

0.755

Female

10

5

Age, years

≤60

29

14

0.890

0.345

>60

14

11

Virus infection

HBV

35

23

0.698

0.403

HCV

2

0

None

6

2

AFP (ng/ml)

≤200

20

8

1.374

0.241

>200

23

17

Cirrhosis

Present

30

18

0.038

0.846

Absent

13

7

Tumor size, mm

≤50

26

13

0.837

0.360

>50

15

12

TNM stage

I or II

25

20

3.375

0.066

III or IV

18

5

Tumor differentiation

Well

6

10

6.591

0.037 ^*

Moderate

28

11

Poor

9

4

Tumor number

Solitary

32

22

1.784

0.182

Multiple

11

3

Tumor encapsulation

Intact

11

15

7.930

0.005 ^*

Absent or not intact

32

10

Vascular invasion

Present

23

6

5.620

0.018 ^*

Absent

20

19

Early recurrence

Yes

25

8

4.324

0.038 ^*

No

18

17

Intra-hepatic metastasis

Present

16

5

4.997

0.025 ^*

Absent

17

20