Table 4 Risk of subtype-specific breast cancer in relation to family history of breast cancer compared with benign breast disease control

Pathology

DCIS

1.27 (0.36 to 4.46)

0.704

1.30 (0.38 to 4.43)

0.679

Invasive cancer

2.22 (1.32 to 3.75)

0.003

2.26 (1.36 to 3.75)

0.002

Tumor size^c

≤2 cm

1.87 (0.92 to 3.80)

0.084

1.94 (0.97 to 3.87)

0.061

>2 cm

2.29 (1.22 to 4.29)

0.010

2.34 (1.28 to 4.30)

0.006

Lymph node involvement^c

Negative

2.60 (1.42 to 4.75)

0.002

2.56 (1.43 to 4.57)

0.001

Positive

2.07 (1.05 to 4.08)

0.036

2.14 (1.10 to 4.15)

0.025

Hormone receptor status^c

Negative

3.05 (1.45 to 6.41)

0.003

2.76 (1.35 to 5.64)

0.005

Positive

2.09 (1.16 to 3.78)

0.014

2.19 (1.23 to 3.89)

0.008

Molecular subtype^c

Triple negative

3.35 (1.43 to 7.88)

0.005

3.17 (1.38 to 7.28)

0.007

Non-triple negative

2.14 (1.21 to 3.80)

0.009

2.20 (1.27 to 3.82)

0.005