Table 3 Applications of adjuvant treatment with interferon in IFN group
Study | Intervention | Follow-up (months) |
|---|---|---|
Ikeda K (2000) | 10 patients received natural IFN-β 6×106 twice a week for 36 months | 25.0 |
Kubo S (2000) | 15 patients received 6×106 IFN-α intramuscularly every day for 2 weeks, then three times weekly for 14 weeks, and finally twice weekly for 88 weeks. | 60.0 |
Shiratori Y (2003) | 49 patients received 6×106 IFN-α intramuscularly three times weekly for 48 weeks. | 85.2 |
Lin SM (2004) | 20 patients received 3×106 IFN-α 2b intramuscularly three times weekly for 24 months. | 27.0 |
Piao CY (2005) | 30 patients orally received 100 mg of lamivudine daily after HCC treatment. | 24.0 |
Mazzaferro V (2006) | 76 patients received 3×106 IFN-α 2b three times weekly for 48 weeks. | 45.0 |
Sun HC (2006) | 118 patients received 3×106 IFN-α intramuscularly twice a week for 2 weeks and then 5×106 three times weekly for 18 months. | 36.5 |
Lo CM (2007) | 40 patients received 10×106/m2 IFN-α 2b subcutaneously three times weekly for 16 weeks. | 30.0 |
Li M (2009) | 108 patients received IFN-α 2b 3×106 three times weekly by intramuscular injection one week. | 24.8 |
Li N (2010) | 43 patients received lamivudine with or without adefovir dipivoxil. | 24.0 |
Ishikawa (2012) | 29 patients received PEG-IFN α-2b/ribavirin after curative HCC treatment. | 36.0 |