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Table 3 Characteristics of six patients with local recurrence after intersphincteric resection (ISR)

From: Analysis of the clinical factors associated with anal function after intersphincteric resection for very low rectal cancer

Patient

TNM

T stage

Histological type

Surgical procedure

Distal resection margin, mm

Circumferential resection margin, mm

Localization

Distant metastases

Treatment

Outcome

1

IIA

T3

G2

tISR + pESR

7

2

Pelvic wall

NS

CRT

45 months, O

2

IIIB

T3

G2

sISR + pESR

25

2

Pelvic wall

NS

CRT

70 months, S

3

IIIB

T3

G2

pISR

12

5

Pelvic wall

Bone, lung

Cx

31 months, P

4

IIA

T3

G2

pISR

10

0.5

Lateral node

Adrenal gland

Cx

36 months, P

5

I

T2

G1

pISR

3

6

Anastomosis

NS

APR

22 months, S

6

IIB

T3

G1

pISR

3

0.5

Lateral node

NS

CRT

17 months, S

  1. Distal resection margins and circumferential resection margins were measured on the histological slides.
  2. APR = abdominoperineal resection; CRT = chemoradiotherapy; Cx = chemotherapy; ESR = external intersphincteric resection; ISR = intersphincteric resection; NS = not stated; O = other origin of death; P = primary death; S = survived.