Evaluation of the immune factors in the tumor environment before and after the treatment of cetuximab combined with chemotherapy

Table 5 The correlation of expression of immune factors and clinical efficacy before treatment was examined by the Spearman’s correlation analysis

		Clinical efficacy	CD8	IL-2	VEGF	TNF-α
CD8	Correlation coefficient	−0.116
	P value	0.719
	Sample size	12
IL-2	Correlation coefficient	0.093	0.117
	P value	0.774	0.717
	Sample size	12	12
VEGF	Correlation coefficient	0.090	0.213	−0.265
	P value	0.781	0.507	0.405
	Sample size	12	12	12
TNF-α	Correlation coefficient	0.131	0.055	0.629	0.130
	P value	0.684	0.866	0.028^a	0.688
	Sample size	12	12	12	12
TGF-β	Correlation coefficient	0.277	−0.413	0.312	−0.519	0.257
	P value	0.383	0.182	0.323	0.084	0.420
	Sample size	12	12	12	12	12

ISSN: 1477-7819