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Table 1 Clinicopathologic variables in 108 patients with hepatocellular carcinoma

From: Correlation analysis of preoperative serum alpha-fetoprotein (AFP) level and prognosis of hepatocellular carcinoma (HCC) after hepatectomy

Variable

AFP negative

AFP low

AFP high

Age at diagnosis, years, mean ± SD

52.5 ± 8.6

52.1 ± 7.8

52.7 ± 6.9

Gender, male/female

34/7

20/8

34/5

HBsAg-positive

37

27

38

Family history of liver cancer

6

3

8

Family history of HBV infection

11

7

16

No family history of liver disease

24

18

15

Tumor number =1

35

21

28

Tumor number ≥2

6

7

11

Tumor diameter, cm, mean ± SD

5.9 ± 6.9

5.2 ± 4.5

5.0 ± 3.9

Portal vein tumor thrombus

   

No

37

23

33

Yes

4

5

6

Adjacent tissue invasion

   

No

39

24

34

Yes

2

4

5

Lymph node invasion

   

No

39

24

37

Yes

2

4

2

Cell differentiation*

   

Well-differentiated

14

1

1

Moderate

24

25

33

Poor

3

2

5

Microscopic invasion*

   

No

25

7

8

Yes

16

21

31

Nerve invasion

   

No

39

25

39

Yes

2

3

0

Lymph node metastasis

   

No

39

27

37

Yes

2

1

2

Fibrosis

   

0 to 4 points

2

3

2

5 to 6 points

39

25

37

Recurrence rate, n (%)

   

1-year

7 (17.1)

6 (21.4)

10 (25.6)

2-year*

8 (19.5)

7 (25.0)

18 (46.2)

Survival rate, n (%)

   

6-month

38 (92.7)

25 (89.3)

33 (84.6)

12-month

35 (85.4)

24 (85.7)

28 (71.8)

18-month*

35 (85.4)

22 (78.6)

23 (59.0)

24-month*

33 (80.5)

20 (71.4)

21 (53.8)

  1. Results are presented as number of patients unless stated otherwise. *P <0.05. AFP, alpha-fetoprotein.