From: Prognostic analysis of early-stage squamous cell carcinoma of the vulva
Risk factors | Overall survival | Progression-free survival | |||
---|---|---|---|---|---|
Number of patients | OS at five years (%) | Log-rankPvalue | PFS at five years (%) | Log-rankPvalue | |
Age (years) | Â | Â | 0.661 | Â | 0.941 |
 ≤50 | 6 | 83.3 |  | 83.3 |  |
 50 to 60 | 14 | 91.7 |  | 91.7 |  |
 >60 | 15 | 78.6 |  | 71.4 |  |
FIGO stage | Â | Â | 0.733 | Â | 0.637 |
 1a | 5 | 100 |  | 100 |  |
 1b | 30 | 81.5 |  | 77.8 |  |
Tumor location | Â | Â | 0.047 | Â | 0.039 |
 Lateral | 9 | 64.8 |  | 66.7 |  |
 Medial | 26 | 87.0 |  | 87 |  |
Grade | Â | Â | 0.493 | Â | 0.458 |
 I | 26 | 84.0 |  | 84.0 |  |
 II | 7 | 62.5 |  | 83.3 |  |
 III | 2 | 50.0 |  | 50.0 |  |
Morphology | Â | Â | 0.028 | Â | 0.042 |
 cauliflower | 26 | 91.3 |  | 87.0 |  |
 nodular | 9 | 66.7 |  | 62.5 |  |
Lymph node clinical state | Â | Â | 0.014 | Â | 0.022 |
 not increased and active | 16 | 73.3 |  | 66.7 |  |
 increased and hard | 17 | 92.9 |  | 92.9 |  |
 syncretic | 2 | 50.0 |  | 50.0 |  |
invasion depth (mm) | Â | Â | 0.842 | Â | 0.918 |
 ≤1 | 5 | 100 |  | 100 |  |
 1 to 4 | 10 | 80.0 |  | 70.0 |  |
 5 to 7 | 10 | 62.5 |  | 62.5 |  |
 >7 | 10 | 75.0 |  | 75.0 |  |
Surgical treatment | Â | Â | 0.005 | Â | 0.003 |
Local excision | 2 | 83.9 | Â | 83.9 | Â |
Radical vulvectomy and en bloc resection of inguinofemoral lymph nodes | 12 | 81.8 | Â | 72.7 | Â |
Radical vulvectomy and en bloc resection of inguinofemoral and pelvic lymph nodes | 21 | 50.0 | Â | 50.0 | Â |