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Table 2 Expression of MT isoforms in lung cancers and cancer-surrounding tissues a,b

From: Expression of metallothionein and Nrf2 pathway genes in lung cancer and cancer-surrounding tissues

 

Lung cancer tissue

Peri-cancer tissue

MT-1A

11.59 ± 1.16c

47.03 ± 0.26

MT-1E

0.52 ± 0.23c

4.16 ± 0.96

MT-1G

0.66 ± 0.18c

1.71 ± 0.55

MT-2A

12.68 ± 1.76c

33.88 ± 8.87

MT-3

0.86 ± 0.27

1.52 ± 0.72

MT-4

0.06 ± 0.02

0.18 ± 0.07

MTF1

11.76 ± 3.52c

34.56 ± 12.56

  1. Abbreviations: MT metallothionein; MTF Metal transcription factor.
  2. aTotal RNA was extracted from surgically removed lung cancers (n = 62 to 80) and cancer-surrounding tissues (n = 21 to 38), and the expression of MT isoforms was examined via real-time reverse transcription (RT)-PCR.
  3. bData are expressed as a percentage of the expression of the housekeeping gene glyceraldehyde 3-phosphate dehydrogenase.
  4. cSignificantly different from cancer-surrounding tissues p < 0.05.
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World Journal of Surgical Oncology

ISSN: 1477-7819

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