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Table 1 Characteristics of the studies included in the meta-analysis

From: Radiofrequency ablation versus hepatic resection for the treatment of early-stage hepatocellular carcinoma meeting Milan criteria: a systematic review and meta-analysis

Study Research period RFA (n) HR (n) Trial type Tumor diameter (cm) Grade
Chen et al. 2006 [15] 1999–2004 71 90 RCT ≤5 A
Cho et al. 2005 [25] 2000–2002 99 61 NRCT ≤5 B
Guglielmi et al. 2008 [26] 1996–2006 109 91 NRCT ≤3 B
Guo et al. 2013 [27] 2002–2007 94 102 NRCT ≤5 B
Hasegawa et al. 2008 [28] 2000–2003 3022 2857 NRCT ≤3 B
Hiraoka et al. 2008 [29] 2000–2007 105 59 NRCT 3–5 B
Hong et al. 2005 [19] 2000–2003 55 55 NRCT ≤4 B
Huang et al. 2011 [14] 2000–2005 413 648 NRCT ≤3 B
Lu et al. 2006 [30] 2002–2005 51 54 RCT ≤3 A
Lupo et al. 2007 [24] 2003–2004 42 60 NRCT 3–5 B
Ueno et al. 2009 [31] 2000–2005 155 123 NRCT ≤5 B
Vivarelli et al. 2004 [20] 1998–2005 79 79 NRCT ≤5 B
  1. HR hepatic resection, NRCT nonrandomized controlled trial, RCT randomized controlled trial, RFA radiofrequency ablation.