Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

Table 5 Analysis of the relationship between the two groups in the grade of neurotoxicity using logistic ordinal regression ^a

		Regression coefficient	Standard error	Wald	Degree of freedom	P value	95% confidence interval
		Regression coefficient	Standard error	Wald	Degree of freedom	P value	Lower limit	Upper limit
	[Grade = 0.00]	−1.444	0.281	26.388	1	0.000	−1.995	−0.893
Dependent variable	[Grade =1.00]	−0.133	0.246	0.292	1	0.589	−0.616	0.350
	[Grade = 2.00]	1.135	0.274	17.124	1	0.000	0.598	1.673
Independent variable	[Class = 1.00]	−0.770	0.334	5.317	1	0.021	−1.425	−0.116
	[Class = 2.00]	0.000

^aThe logistic model was successfully constructed, demonstrated by χ²= 5.402 and P = 0.020. The regression coefficient was −0.770, thus the odds ratio of neurotoxicity in the experimental group was 2.16, suggesting the probability of occurrence of low-grade neurotoxicity (grade 0 and 1) in the experimental group was significantly higher than that in the control group.

ISSN: 1477-7819