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Table 1 Neurotoxicity grading scales

From: Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors

Standard setting unit

Grade 1

Grade 2

Grade 3

Grade 4

NCI-Sanofi criteria

Paresthesias or dysesthesias of short duration that resolve and do not interfere with function

Paresthesias or dysesthesias interfering with function but not activities of daily living

Paresthesias or dysesthesias with pain or functional impairment that also interfere with activities of daily living

Persistent paresthesias or dysesthesias that are disabling or life-threatening

  1. NCI, National Cancer Institute.