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Figure 1 | World Journal of Surgical Oncology

Figure 1

From: The pathologic response of resected synovial sarcomas to hyperthermic isolated limb perfusion with melphalan and TNF-α: a comparison with the whole group of resected soft tissue sarcomas

Figure 1

Macroscopic and microscopic features of two SSs after treatment with TM-HILP. (A-C) Case number 5, nonresponder. (A) 7.9 cm SS of the foot with a regression of 65% after TM-HILP. (B) Necrotic areas with yellow tumor changes and viable tumor residues in proximity to a removed tendon segment (*). (C) Histopathology of a predominately viable tumor next to the cross-section of a tendon (*). The tumor infiltrates the inked margin (arrow). (D-F) Case Number 6, responder. (D) 9.0 cm SS of the lower leg with a regression of 99%. (E) Abundant areas of yellow necrosis mixed with glassy-white sclerotic areas after therapy. (F) Histopathology revealed only a few small foci of viable tumor (arrows). These residues were completely removed.

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