Prognostic factors affecting the clinical outcome of carcinoma ex pleomorphic adenoma in the major salivary gland

Table 3 Influence of clinical and pathologic parameters on recurrence and survival

Variables	P value
Variables	Locoregional recurrence	Distant metastasis	Tumor- specific survival	Overall survival
Age (<55/≥55)	0.193	0.881	0.090	0.033
Sex	0.941	0.543	0.340	0.183
Primary site	0.361	0.318	0.893	0.650
(parotid/submandibular, sublingual)	0.361	0.318	0.893	0.650
Pleomorphic adenoma operation history (no/yes)	0.955	0.840	0.383	0.564
Malignant component (S/M/A/O)*	0.990	0.601	0.842	0.682
Histological grade	0.417	0.004	0.020	0.011
(low, intermediate/high)	0.417	0.004	0.020	0.011
Invasiveness	0.012	0.015	0.001	0.003
(non-invasive, minimally invasive/invasive)	0.012	0.015	0.001	0.003
Carcinomatous component	0.146	0.401	0.318	0.482
(<50%/>50%)	0.146	0.401	0.318	0.482
T stage (1, 2/3, 4)	<0.001	0.712	0.002	0.004
Lymph node involvement	0.008	<0.001	<0.001	<0.001
(negative/positive)	0.008	<0.001	<0.001	<0.001
Clinical stage	0.001	0.076	<0.001	<0.001
(I, II/III, IV)	0.001	0.076	<0.001	<0.001
Perineural invasion	0.086	0.020	<0.001	<0.001
(negative/positive)	0.086	0.020	<0.001	<0.001

Note: * S, Salivary duct carcinoma; M, Myoepithelial carcinoma; A, Adenocarcinoma not otherwise specified; O, Others.
Slashes mean comparison between the categorical variables in each side of slashes. Commas indicate the combination of the categories for comparison with others.

ISSN: 1477-7819